iScience - Mobile Member Profile - Shreekant Deshpande

Personal Info

First Name Shreekant
Last Name Deshpande
Gender Male
Birthday August 17, 1979

About

University/Institute Central Drug Research Institute
Department Medicinal Chemistry Division
About me I am fascinated Medicinal Chemist..
<br>Specialization in Medicinal Chemistry with extra emphasis on Synthetic Chemistry
Excellent bench skills with sound knowledge of drug design and development techniques.
Expert in 2D & 3D QSAR, Molecular modeling, Docking & handling big datasets.
Capabilities to extrapolate biological & computational interpretations into organic synthesis.r>Experience of working in a team and capabilities to maintain collaborations.<br>Experience in training undergraduate students with effective communication skills.

Contact Info

Address Mailing Address:
Medicinal & Process Chemistry Division
Central Drug Research Institute>Chattar Manzil Palace, M.G. Marg
Lucknow-226 001, Uttar Pradesh, India
r>Permanent Address:
S. K. Deshpande
Ward No.1, Mudhol-587313 E. mail: srideshpande@gmail.com
Dist. Bagalkot, Karnataka srideshpande@cdri.res.in (working)r>

Education

Thesis title Synthesis, biological evaluation and QSAR studies of antimalarial agents
Education Ph.D (Medicinal Chemistry): “Synthesis, Biological Evaluation and QSAR Studies of Novel Antimalarial Agents”. To be submitted by June 2010 to Jawaharlal Nehru University, New Delhi, India.r>Supervisors: Dr. Y. S. Prabhakar & Dr. S. B. Katti, Scientists, Central Drug Research Institute, Lucknow, India.r>
Master of Pharmacy (Pharmaceutical/ Medicinal Chemistry): (2003-2005) Govt. College of Pharmacy, Bangalore, India.
Bachelor of Pharmacy: (1998–2002) from K.L.E’s College of Pharmacy Belgaum (Rajiv Gandhi University of Health Sciences, Bangalore. Karnataka)

Presentation

Oral Presentations 1. Oral presentation on “Synthesis of rationally designed 4-aminoquinoline derived antimalarials” in JNOST-2009 held in IIT Kanpur during Dec 4-7th 2009.
>3. Oral presentation on “Is Feature Selection Essential for ANN Modeling?” in Joint Meeting of 8th International Conference on Mathematical Chemistry and 5th Indo-US Workshop on Mathematical Chemistry” held in Univ. of Minnesota, Duluth, MN, USA during Jun 22-27th 2008.

3. Oral presentation on “Microwave induced modified synthesis of Triaryl imidazole analogs and their biological activity” in Indian Pharmaceutical Congress-2004, Kolkata, India.>
Posters 1. Poster presentation on “The solubility challenge: A prospective and retrospective analysis” in 4th Indo-US Lecture Series on Discrete Mathematical Chemistry” held in Osmania University, Hyderabad during Jan 6– 9th 2009.
2. Poster presentation on “Topological descriptors in modelling antimalarial activity: N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine as prototype” in International conference on the interface of Chemistry- Biology in biomedical research held at BITS-Pilani, Rajastan during Feb 22-24th 2008.<br>3. Poster presentation on “Microwave induced modified synthesis of 4-aryl dihydropyrimidine analogs and their biological activity” in 3rd International Symposium on Current Trends In Drug Discovery Research held at CDRI, Lucknow during Feb 17 - 21st 2007.

Publications

Journal Papers 1. Shreekant Deshpande; Singh R.; goodarzi M.; Katti S.B.; Prabhakar Y. S. Consensus Features of CP-MLR and GA in Modeling HIV-1 RT Inhibitory Activity of 4- Benzyl/benzoyl pyridin-2-one Analogues. Euro. J. Med. Chem (communicated).
2. Shreekant Deshpande; Gupta M. K.; Prabhakar Y. S. Multi-Model Environment as a Rational Approach for Drug Design: An Experience with CP-MLR. The IUP Journal of Chemistry, Vol III(1), 2010. r>3. Shreekant Deshpande; Solomon V. R.; Katti S. B.; Prabhakar Y. S. Topological descriptors in modelling antimalarial activity: N1-(7-chloro-4-quinolyl)-1,4-bis(3-aminopropyl)piperazine as prototype. J. Enzym. Inhbn. Med. Chem, 2009; 24(1); 94. >4. Goodarzi M.; Shreekant Deshpande; Murugesan V.; Katti S. B.; Prabhakar Y. S. Is Feature Selection Essential for ANN Modeling? QSAR Comb Sci. 2009, 28, 1487.
5. Ravi Shankar; Chakravarti B.; Singh U. S.; Ansari M. I.; Shreekant Deshpande, Dwivedi S. K. D.; Bid H. K.; Konwar R.; Kharkwal G.; Chandra V.; Dwivedi A.; Hajela K. Synthesis and Biological Evaluation of 3, 4, 6-Triaryl -2-Pyranones as a Potential New Class of Anti-breast Cancer Agents. Bioorg. Med. Chem 2009, 17(11); 3847.
6. Kumar S.; Shreekant Deshpande; Chandra V.; Kitchlu S.; Dwivedi A.; Nayak V. L.; Konwar R.; Prabhakar Y. S.; Sahu D. P. Synthesis and biological evaluation of 2,3,4-triarylbenzopyran derivatives as SERM and therapeutic agent for breast cancer. Bioorg. Med. Chem. 2009, 17; 6832.r>
(Manuscripts relating to Medicinal chemistry are under preparation)