Dr. Bhupender Singh 28 articles
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Impact of microwave radiations on macrocyclization reactions: solvent free synthesis of 1,4-benzothiazin-3-one derivatives on basic alumina

A rapid transformation of alkyl and arylalkyl amino phenyl thioethers (2-alkylsulphanyl-phenylamine) into 7-substituted 1,4-benzothiazines in presence of basic-alumina under solvent free conditions using microwave irradiation has been described. The specific microwave effects are due to increase in polarity during the course of reaction.

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  • Authors Bhupender S. Chhikara, Vibha Tandon and A. K. Mishra
  • Affiliation Medicinal ­Chemistry ­Research L­aboratory,­ Dr. B. R.­ Ambedkar ­Center for­ Biomedica­l Research­, Universi­ty of Delh­i, Delhi, ­India.
    Department­ of Radiop­harmaceuti­cal Chemis­try, Insti­tute of Nu­clear Medi­cine and A­llied Scie­nces, Delh­i, India.
  • Journal name Heterocyclic Communications
  • Year 2004
  • Volume, Issue 10, 5
  • Page Number 441-446
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